PRP and Stem Cell Injections for Buttock Pain offered in Estero, Florida.

Do you suffer from nagging or sharp pain in your buttock that makes it hard to sit, walk, or enjoy daily activities?

Buttock pain can be especially frustrating because it often has more than one potential source. This results in patients going from doctor-to-doctor injection various locations to find the right target.

At Integrative Rehab Medicine, we understand that buttock pain is notoriously difficult to diagnose, which is why we use a comprehensive approach that combines a detailed physical examination with advanced imaging to uncover the true cause of your pain. After we identify the root causes of your buttock pain we will treat them with advanced non-surgical and regenerative therapies designed to restore tissue health and function.

Resolve Hip Pain and Regain Your Function

Common Symptoms of Buttock Pain

  • Deep, aching pain in the buttock, sometimes radiating to the thigh
  • Pain that worsens with prolonged sitting or walking
  • Tingling or numbness when nerve compression is involved
  • Weakness in surrounding muscles due to chronic irritation or instability

Causes of Buttock Pain

Buttock pain can stem from multiple structures, and often more than one issue contributes to the discomfort.

  • Hip Joint Problems – Conditions such as hip osteoarthritis (OA) or hip tendonitis/tendinopathy can cause localized buttock pain due to joint degeneration or small tendon tears that irritate surrounding tissues.
  • Sacroiliac (SI) Joint Dysfunction – Inflammation or instability of the SI joints, which connect the spine to the pelvis, often causes buttock pain that may mimic sciatica.
  • Lumbar Spine Nerve Compression – Spinal stenosis, herniated discs, or degenerative changes in the lumbar spine can compress nerves, leading to referred pain in the buttock.
  • Soft Tissue Injuries – Muscle strains or bursitis in the gluteal region may also contribute.

Because of these overlapping causes, proper diagnosis is essential to ensure effective treatment.

Accurate Diagnosis Is Key

At Integrative Rehab Medicine, we use a comprehensive diagnostic approach to identify the possible causes including spinal arthritis, stenosis, disc injury, tendon injury, tendonitis, hip arthritis and biomechanical dysfunction. This includes:

  • Comprehensive physical examination assessing the hip, spine, and SI joints
  • Ultrasound or MRI imaging to detect tendon tears, bursitis, disc injury or stenosis
  • X-rays to evaluate arthritis and joint space narrowing

This allows us to tailor a comprehensive regenerative treatment plan specific to your injury and functional goals.

There are treatment options for hip bursitis beyond repeated steroid injections.

Do You Want to Resolve Hip Pain and Restore Function?

Regenerative Treatment Options

We specialize in non-surgical regenerative orthopedic solutions designed to stimulate the body’s natural healing processes and restore joint health. Our goal is to provide long-term pain relief by targeting the underlying cause of your buttock pain:

  • Platelet-Rich Plasma (PRP) – Uses your body’s growth factors to heal tendon tears, strengthen tissues, and reduce inflammation in the hip or SI joints. PRP can also be used to treat the facet joints of the spine or damaged/ inflamed nerves.
  • Prolotherapy – Stimulates repair and stabilizes ligaments around the pelvis, hips, and SI joints to restore function and reduce pain.
  • Stem Cell Therapy (Bone Marrow Derived) Provides regenerative cells that can repair damaged cartilage, tendons, and ligaments for patients with arthritis or chronic injuries. 
  • Discseel – Discseel Procedure is an injection-based treatment that utilizes natural Fibrin glue to seal spinal discs. Disc tears are a common cause of chronic back and buttock pain. The Discseel® Procedure is the only treatment proven to seal spinal discs and encourage disc healing.

Frequently Asked Questions

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Are You a Candidate for Regenerative Hip Treatment

Complementary Treatments

In addition to regenerative injections, we incorporate evidence-based complementary therapies to enhance recovery and long-term hip function:

  • 1-on-1 Physical Therapy – Work directly with a licensed physical therapist to strengthen and re-educate muscles of the hip and spine. This neuromuscular reprogramming helps restore movement patterns and reduce reinjury risk.
  • Nutritional Therapy & Supplements – Proper nutrition supports the healing of connective tissue. We offer personalized supplement protocols and dietary guidance to optimize collagen synthesis, reduce inflammation, and improve overall recovery.
  • Giga Laser Therapy – Our Giga Laser, one of the most powerful therapeutic lasers in the world, delivers high-dose red and infrared light therapy over large areas. This boosts mitochondrial activity and promotes rapid tissue healing and collagen formation.

Why Choose Integrative Rehab Medicine?

  • Minimally invasive treatments backed by clinical science
  • Comprehensive evaluation determining the root cause of your pain
  • Personalized regenerative treatment plans specific to your injury and functional goals
  • Avoid surgery and reduce downtime – many patients are back to activity 3-4 weeks after treatment
  • Expert clinicians with extensive experience in regenerative and rehabilitative medicine

Take Control of your Buttock Pain

Buttock pain can interfere with your ability to sit comfortably, stay active, or even sleep. With accurate diagnosis and advanced regenerative treatments, you don’t have to live with this discomfort.

Schedule your consultation today with Integrative Rehab Medicine and take the first step toward long-lasting relief.

Schedule your Consult with an Estero Hip Pain Specialist

References

  1. Dallari D, Stagni C, Rani N, et al. Ultrasound-Guided Injection of Platelet-Rich Plasma and Hyaluronic Acid, Separately and in Combination, for Hip Osteoarthritis: A Randomized Controlled Study. The American Journal of Sports Medicine. 2016;44(3):664-671. doi: 10.1177/0363546515620383
  2. Fitzpatrick J, Bulsara MK, O’Donnell J, Zheng MH. Leucocyte-Rich Platelet-Rich Plasma Treatment of Gluteus Medius and Minimus Tendinopathy: A Double-Blind Randomized Controlled Trial With 2-Year Follow-up. Am J Sports Med. 2019 Apr;47(5):1130-1137. doi: 10.1177/0363546519826969. Epub 2019 Mar 6. PMID: 30840831.
  3. Fitzpatrick J, Bulsara MK, O’Donnell J, McCrory PR, Zheng MH. The Effectiveness of Platelet-Rich Plasma Injections in Gluteal Tendinopathy: A Randomized, Double-Blind Controlled Trial Comparing a Single Platelet-Rich Plasma Injection With a Single Corticosteroid Injection. Am J Sports Med. 2018 Mar;46(4):933-939. doi: 10.1177/0363546517745525. Epub 2018 Jan 2. PMID: 29293361.
  4. Giorgino, R., Alessandri Bonetti, M., Migliorini, F. et al. Management of hip osteoarthritis: harnessing the potential of mesenchymal stem cells—a systematic review. Eur J Orthop Surg Traumatol 34, 3847–3857 (2024). https://doi.org/10.1007/s00590-024-04089-0
I have never left a review regarding a phone call, but there is always a first. I have called this office multiple times asking every question that comes to mind for my husband with back issues. And every time I called I have spoken to Amanda Nagle. She took all of my calls so patiently and kind answering all my questions. I was never rushed most importantly she put me at ease. I have called multiple offices finding a good fit for my husband. And I’m comfortable enough just speaking to, Amanda that this is the right place for him. If the front office “the face of the office” is like this, I know that the rest is amazing.
Anybody going through chronic pain knows the frustration. What did PRP do for me? Pain went from a 9 to a 2 and sometimes 0. Activity? Before I couldn't do anything and was in pain. After, some limitations but no lasting pain. For example, I'm jump roping and running but no load bearing above 30 pounds. It's a learning pain. PRP improved my health. At Integrative Rehab Med. they are absolutely 100% caring and professional. I am thankful for Dr. Sebastian and his professional staff!
I am currently one month removed from my procedure from Dr. Sabastian and his staff. All of my consistent pain stop. Physical therapy is continuing under there direction.

With more positive improvement coming long term my advice why wait call or visit them. Integrative Rehab Medicine is the very best non-surgical treatment of the spinal discs.

I excited about my future living without pain. Make this appointment your health will Thank you later.

Chris Drikakis
A fellow golfer and Vietnam veteran
Response from the owner:Thank you so much, Chris, for taking the time to share your experience—and for your service as a Vietnam veteran. We’re truly honored to be part of your healing journey.

We’re thrilled to hear that just one month after your non-surgical spinal disc procedure, your consistent pain has resolved and that you’re continuing to make progress. At Integrative Rehab Medicine, our mission is to help patients avoid unnecessary spine surgery by offering advanced, evidence-based treatments for chronic back and neck pain, including non-surgical disc repair options such as Discseel® and PRP.

Your story highlights exactly why we focus on treating the underlying cause of disc-related pain—not just masking symptoms—and why so many active patients, including golfers and veterans, seek out non-operative spine care with us. We’re excited about your continued improvement and long-term recovery.

https://irehabmed.com/va

Thank you again for your kind words.
Im very fortunate to met the Doctor Sebastian when he came to Margaritaville Cancun riviera Maya. He treated my knee after two surgeries in my right knee without result. The time Doctor Sebastian attended me I was in pain every day and taking anti inflammatory every 2 days, since he treated me my knee and movement change drastically at level I don’t taking any more medication he is a really master pro, for sure I’ll will see him early next year for a second treatment to keep improving my recovery thanks Doctor to came across my live 🙏🙏🙏🙏Hernan Mota
I had suffered from degenerating discs, bulging discs and arthritis in my lower back for 25 years. I initially went to Integrative Rehab Medicine as they offered DiscSeel, which I heard was a great option for me. Although I was a candidate for this, I opted for PRP and prolotherapy. My recovery was a bit longer than o hoped at 8-12 weeks but I am finally pain free and only get discomfort for a day or so with movements that may have had me down for 2 months. The care in office was wonderful with great follow ups. They also allowed my personal trainer into my physical therapy to ensure we were on the same page with my recovery. Five stars and I would highly recommend.
Response from the owner:Thank you so much for sharing your journey. We truly appreciate your trust after living with degenerative discs, bulging discs, and lumbar arthritis for more than 25 years.
While Discseel® can be an excellent option for certain patients, we’re glad you found success with platelet-rich plasma (PRP) and prolotherapy—two powerful non-surgical treatments designed to reduce inflammation, support tissue healing, and improve spinal stability. As you experienced, biologic spine treatments often require patience, with healing occurring over weeks to months, but the long-term improvement can be life-changing.
We’re especially happy to hear that you’re now pain-free and that movements which once caused months of setback now result in only brief, mild discomfort. That kind of functional recovery is exactly what we aim for at Integrative Rehab Medicine.
We truly appreciate the recommendation and are honored to be part of your long-term spine health.
I’m so glad that I found Integraive Rehab Medicine and specifically Dr Sebastian. Dr Sebastian was the only doctor who provided a solution to my damaged lower back that made sense and actually worked. After six months after the procedure I can say that Dr Sebastian gave me back the ability to move pain free and enjoy life as I could at my age. He said he is sorry that he couldn’t make me young again, but he and his staff did a miracle for me.
Thank you Integrative Rehab Medicine for changing my life
Response from the owner:Thank you for sharing your experience and for allowing us to play a role in your healing. We are truly grateful that you put your trust in our regenerative medicine approach to treating back pain and improving function. Helping patients feel stronger and more functional is what we do best here at Integrative Rehab Medicine in Estero, Florida. Take care.
I have not been here but I have seen Dr. Shiple in PA. He is one of the world's most flawless injectors! From PRP, Stellate Ganglion Block, Vagus Nerve Block, Hydrodissection etc...

He has gotten me out of a bedbound life.

He does even better when Bruce Hornsby is playing during the session 😁
Response from the owner:Thank you for sharing such kind words about Dr. Brian Shiple! He is indeed one of the most skilled and experienced regenerative injection specialists in the world, and we’re honored to have him on our team here at Integrative Rehab Medicine in Estero, Florida. It’s inspiring to hear how his advanced techniques—like PRP, Stellate Ganglion Block, Vagus Nerve Block, and ultrasound-guided hydrodissection—helped you reclaim your health and quality of life.
My wife and I traveled from Wisconsin to get my two herniated discs in lower back treated with ozone/prp. I could not be happier with how everything went. Dr. Sebastian and his team are wonderful. From the very beginning of sending in my mri results to after the procedure was so efficient and organized. Everyone at this clinic is very informative, professional and just the nicest people to be around. Especially for me being nervous having never had any back procedures done....they made it so much easier. I am looking forward to my continued healing. You have a raving fan in Wisconsin now and I'd only come to your clinic if I ever need future procedures! Thanks to everyone that helped me!
Response from the owner:Thank you so much for sharing your experience and for traveling all the way from Wisconsin to southwest Florida for your spinal treatments in our Estero clinic. We’re thrilled to hear that your ozone and PRP treatments for herniated discs in your lower back went smoothly and that our team helped you feel comfortable throughout the process. At Integrative Rehab Medicine, we strive to make every step — from MRI review to post-procedure care — efficient, professional, and reassuring. We’re grateful for your trust, excited to see your continued healing, and honored to have a raving fan in Wisconsin!
Dr.Sebastian Klisiewicz, was very nice and helpful.He explained my diagnosis very clearly and help me to choose the best treatment for me. Thank you very much for all your help.
Response from the owner:Thank you, Alicia! We’re so glad to hear that you had a positive experience at our Estero clinic. At Integrative Rehab Medicine, we take pride in carefully diagnosing the root cause of pain and offering clear guidance on the best treatment options. It’s wonderful to know you felt supported throughout the process.
2 bouts of pt over 2 years couldn't resolve my back/ leg problem. 1st procedure at IRM: immediate relief within 24 hrs.
Response from the owner:Thank you for sharing your experience! We’re so glad that your first procedure here at our Estero clinic brought such quick relief. At Integrative Rehab Medicine, we specialize in accurately diagnosing the root cause of pain and providing targeted treatments to help patients return to an active, pain-free life.