Southwest Florida's Leading Experts in Regenerative Medicine

Treating Spine, Joint Pain, and Neuropathy by Advanced Regenerative Medicine and Rehabilitation

Our pain treatment and rehabilitation clinic is centrally located in Estero Florida. Servicing Naples, Bonita Springs, Fort Myers, Cape Coral, Boca Raton, Coral Gables, Palm Beach, Fort Lauderdale & Miami Beach

Doctor shows a hologram of a person on a blue background.

A non-surgical, whole person approach to pain management, specializing in regenerative treatment for chronic pain.

We are an Integrative Physical Medicine & Rehabilitation clinic located in Estero, FL. We offer a comprehensive team approach to help patients eliminate pain, restore function and achieve a state of health and wellness. By combining advanced regenerative medicine with rehabilitation, nutrition and integrative medicine,  we provide the best healing experience in Southwest Florida.

Patients From Around The World

Learn Why Doctor Sebastian is Leading
the Way in Regenerative Medicine:

Advanced Regenerative Therapy In Southwest Florida

A Pain Relief Plan Just For You

Finding the right diagnosis is crucial to your treatment – and it’s where everything begins.

Too many patients come to us after years of guessing, trial-and-error treatments, or one-size-fits-all approaches that never addressed the root cause of their pain. We know that no two cases are the same, which is why we never rush to conclusions. From your very first visit, we strive to ensure that each treatment plan is comprehensive and tailored specifically to YOU – not a generic protocol, but a roadmap built around your unique condition, goals, and healing potential.

You’ll receive a thorough evaluation through the integrated lenses of osteopathic, functional, regenerative, and rehabilitative medicine, along with a detailed physical exam where we assess not just the area of pain, but your entire musculoskeletal system, movement patterns, and functional limitations. Only then, with a complete and accurate diagnosis in hand, can we design the most effective regenerative treatment plan to help you heal and get back to the life you want to live.

Photo of a doctor treating a patients shoulder pain

Find Relief For Your Symptoms

Back pain relief, shoulder pain relief, knee pain relief…What are your symptoms?

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We are leaders in non-surgical relief for common problems and look at your pain from a holistic, comprehensive approach. We’re here to ensure you heal!

  • Neck Pain Treatment
  • Shoulder Pain Treatment
  • Elbow, Wrist & Hand Pain Treatment
  • Back and Spine Pain Treatment
  • Hip Pain Treatment
  • Knee Pain Treatment
  • Foot & Ankle Pain Treatment
  • Neuropathy Pain Treatment
  • Hypermobility Treatment

Physical Therapy Compliments our Regenerative Treatment

Regaining your function with Physical Therapy

Therapeutic exercise, designed to improve the patient’s function and decrease disability, differs from traditional exercise as it takes into account the patient’s pain, injuries, and functional impairments. Therapeutic exercise helps to improve the patient’s functional condition and general health, and it is a key part of comprehensive treatment at our practice.

Recent Blog Posts

Long-Term Results of PRP for Rotator Cuff Tears — Healing That Lasts – Two-Year Study

Study:A 2-year prospective study by Prodromos et al. (2021) examined patients with chronic rotator cuff tendinopathy and variable tears who had not improved with therapy. ...
Read More →

Perineural Platelet-Rich Plasma (PRP) for Diabetic Peripheral Neuropathy — Randomized Trial Shows Durable Benefit

Study:A prospective randomized clinical trial (Hassanien et al., Pain Medicine, 2020) evaluated ultrasound-guided perineural PRP for painful diabetic peripheral neuropathy (DPN). Sixty adults with type ...
Read More →

Adipose-Derived Stem Cells for Rotator Cuff Tears — MRI-Confirmed Tendon Regeneration and Long-Term Improvement

Study:A 2-year prospective study (Jo et al., Arthroscopy, 2020) evaluated the use of autologous adipose-derived stem cells (AD-MSCs) for partial-thickness rotator cuff tears. Nineteen patients ...
Read More →

Long-Term Results of PRP for Rotator Cuff Tears — Healing That Lasts – Two-Year Study

Study:A 2-year prospective study by Prodromos et al. (2021) examined patients with chronic rotator cuff tendinopathy and variable tears who had not improved with therapy. ...
Read More →

Perineural Platelet-Rich Plasma (PRP) for Diabetic Peripheral Neuropathy — Randomized Trial Shows Durable Benefit

Study:A prospective randomized clinical trial (Hassanien et al., Pain Medicine, 2020) evaluated ultrasound-guided perineural PRP for painful diabetic peripheral neuropathy (DPN). Sixty adults with type ...
Read More →

What Our Patients Say:

After dealing with neck and back issues stemming from 21 years as a Naval Helicopter Aircrewman and trying multiple treatments and interventions, the Discseel procedure has been the most favorable treatment I've experienced. I was referred to Dr. Sebastian through the VA Community Care Program, and I am grateful that I was connected with him and his team. Dr. Sebastian, at Integrative Rehab Medicine, has been outstanding throughout the entire process. He is professional, knowledgeable, and takes the time to thoroughly explain every aspect of the procedure, recovery, and expected outcomes. He has always addressed my questions and concerns with patience and honesty, which gave me confidence in my treatment decisions. I also want to recognize Suzanne, Floyd, Michelle, and Kristine. From my first interaction with the office through follow-up care, they have been welcoming, professional, and genuinely caring. They made me feel like family rather than just another patient. Their positive attitude, responsiveness, and attention to detail made every visit a pleasant experience. The procedure has provided meaningful improvement in my symptoms and quality of life. While I still have some lingering issues that I continue to work through, I am grateful for the progress I've made and for the exceptional care I received from Dr. Sebastian and his entire team. I highly recommend Dr. Sebastian and his staff at Integrative Rehab Medicine to anyone seeking treatment options for neck or back conditions.
Sumer Matharu
5 days ago
I had a 3 year old major herniation in my L4-L5 and medium herniation in my L5-S1 discs. I tried everything - physio, chiro, decompression, but it seemed like everyone just wanted me to keep coming back and I constantly kept getting reinjured and honestly a bit fatigued. I was finally contemplating surgery because I was not able to carry out daily life. I finally found Dr. Sebastian on youtube and reached out. He was great in the initial virtual consult. Then I flew in from Canada and went for an ozone injection in both discs. That helped. A few months later I went in for discseel with exosomes, and I feel like a new person. Each time they also included the PRP along the facet joints which I am sure will have their own benefits. I stayed on top of my rehab and workouts, especially walking everyday. I am still not back to 100% but being back to 80% is still amazing considering I was having a hard time even walking, sitting, standing, or picking up my kids. Now I am back at the gym and slowly rebuilding my pre-injury strength. There are small flare ups but they go away in a day or two, and I am learning to avoid certain workouts and movements. Dr. Sebastian and his team including Michelle, Kristine, Amanda, Floyd, and a few others I didn't get the names of, have been fantastic to work with. They answered all my questions to my satisfaction, and provided the best advice I received. I also found their team had practical knowledge around back mechanics and provided me with resources the doctors I saw before were not even aware of. This was money well spent, and I would recommend it to anyone with annular tears and herniations.
duane austin
2 weeks ago
Doctor explained the procedure, it quick and painless.At two weeks I could feel the difference and ten weeks it’s amazing
john barnette
2 weeks ago
I fractured a vertebrae in my neck while in the Army back in 1990 and after working as an Ironworker by trade, my neck and back were both shot. I’ve done all the things: physical therapy, chiropractic adjustments, massage, injections and even had back surgery. After finding Dr. Klisiewicz, and having the Discseel procedure done on both my neck (4.7.26) and my back (5.13.26) I couldn’t be more pleased. The experience has been nothing short of PERFECT! Veterans have priority scheduling and they even have a veteran advocate/representative (Jason K) right there in their office to help facilitate the VA process. This made the process of getting VA approval quick and almost too easy. This procedure could be life changing for so many veterans who are suffering in pain. I encourage you to not wait and reach out today!
Anibal Vega
3 weeks ago
Very professional, they explained every detail of my treatment, it is a blessing that veterans help each others. Will definitely tell others, which already did to my relative that are suffering with back issue's, will go back for other treatments, thank you Dr. Sebastian.
Daniel Manrique
3 weeks ago
⭐⭐⭐⭐⭐ Outstanding Care for Veterans – Life-Changing Results As a combat-wounded Iraq War veteran who served 29 years in the United States military, I have experienced many healthcare systems throughout my career and since my retirement. Without hesitation, I can say that Integrative Rehab Medicine provides the finest VA-covered medical care I have received in the last nine years. I would like to express my deepest gratitude to Dr. Sebastian Klisiewicz, his exceptional medical team, and Jason "JK" Kinnard, Chief Veteran Officer and Veteran Care Navigator, for their unwavering dedication to veterans and their families. Because of wounds and injuries sustained during my service in Iraq, I have suffered from multiple herniated discs in my spine as well as numerous joint-related conditions. Over the years, I underwent several surgeries, yet I continued to live with chronic pain that significantly affected my quality of life, sleep, mobility, and daily activities. From my very first interaction with Integrative Rehab Medicine, I knew I was in the hands of professionals who genuinely care about veterans. Dr. Klisiewicz took the time to thoroughly evaluate my conditions, explain treatment options, and develop a comprehensive plan focused on long-term improvement rather than temporary relief. After only two procedures—and while still in the recovery process before additional recommended treatments—I can already feel a remarkable difference. My pain levels have decreased significantly, my mobility is improving, and for the first time in years I am sleeping better and experiencing real hope for continued recovery. What truly sets this organization apart is not only their medical expertise but also their commitment to guiding veterans through the VA process. Jason "JK" Kinnard has been absolutely outstanding in helping navigate the system, ensuring that veterans receive the care they deserve with professionalism, compassion, and efficiency. His dedication to serving fellow veterans is extraordinary. Dr. Sebastian Klisiewicz and his entire team exemplify excellence in patient care. They listen, they care, and they deliver results. Their professionalism, compassion, knowledge, and commitment to improving veterans' lives are second to none. For any veteran seeking effective treatment for chronic pain, spinal injuries, joint issues, or rehabilitation services, I strongly recommend Integrative Rehab Medicine. They have helped me achieve progress that I had not experienced despite years of treatment elsewhere. Thank you, Dr. Klisiewicz, Jason "JK" Kinnard, and the entire Integrative Rehab Medicine team for your outstanding service to our veteran community. You are making a real difference in the lives of those who have sacrificed for our nation. Dr. Daniel Manrique, Ph.D. Combat-Wounded Iraq War Veteran Purple Heart Recipient Retired U.S. Military Officer
Alcalli Sabat
3 weeks ago
I had a lower back procedure performed with Interactive Rehab Medicine through the VA. The procedure "Discseel was a success but the VA side trying to get approved was a bumpy road and it's not the VA per say but the wrong people are in the process for approval and that needs to be fixed. I am healing well and the Staff from Interactive Rehab Medicine were very professional and I would recommend this procedure to any veteran with lower back issues in every aspect of outpatient and quick recovery. I still have 1 more month to go to completely heal so we will see. This procedure has made a difference in my life. Thank you Jason Kinnard, Dr. Sebastian Klisiewicz and all the Interactive Rehab Staff for a great job. Keep up the good work and I will be spreading the word. Are there any T-Shirts?
Isaac Cortes
3 weeks ago
Excellent services and staff unlike no other. Im now pain free from my back with no issues. Now would like to address my neck stiffness with PRP treatment injections when fully recovered from my March 19 postop neck revision surgery. Im confident that Dr. Klisiewicz will do a great job just like he did with my ailing back with the discseel procedure. See you soon Doc! 😊
brian feiock
3 weeks ago
I have found Dr. Klisiewicz to be a thoughtful, attentive, accurate, and highly skilled diagnostician/clinician. He performed a spinal disc procedure for me ("Discseel") which resulted in a remarkable degree of improvement in longstanding low back pain with minimal invasiveness, no complications, and a quick recovery. I completely trust his judgement, advice, and procedural capability. My experiences with he and his staff have been reliably positive. I recommend him highly and without reservation.
Carl
3 weeks ago
I had a great experience with Dr. Sebastian and the DISCSEEL procedure. From the consultation through follow-up care, he took the time to explain everything thoroughly and answer all of my questions. His professionalism, expertise, and genuine concern for his patients gave me confidence throughout the process. I also want to thank his staff for their outstanding care and support. I highly recommend Dr. Sebastian to anyone considering the DISCSEEL procedure.