Southwest Florida's Leading Experts in Regenerative Medicine

Treating Spine, Joint Pain, and Neuropathy by Advanced Regenerative Medicine and Rehabilitation

Our pain treatment and rehabilitation clinic is centrally located in Estero Florida. Servicing Naples, Bonita Springs, Fort Myers, Cape Coral, Boca Raton, Coral Gables, Palm Beach, Fort Lauderdale & Miami Beach

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A non-surgical, whole person approach to pain management, specializing in regenerative treatment for chronic pain.

We are an Integrative Physical Medicine & Rehabilitation clinic located in Estero, FL. We offer a comprehensive team approach to help patients eliminate pain, restore function and achieve a state of health and wellness. By combining advanced regenerative medicine with rehabilitation, nutrition and integrative medicine,  we provide the best healing experience in Southwest Florida.

Patients From Around The World

Learn Why Doctor Sebastian is Leading
the Way in Regenerative Medicine:

Advanced Regenerative Therapy In Southwest Florida

A Pain Relief Plan Just For You

Finding the right diagnosis is crucial to your treatment – and it’s where everything begins.

Too many patients come to us after years of guessing, trial-and-error treatments, or one-size-fits-all approaches that never addressed the root cause of their pain. We know that no two cases are the same, which is why we never rush to conclusions. From your very first visit, we strive to ensure that each treatment plan is comprehensive and tailored specifically to YOU – not a generic protocol, but a roadmap built around your unique condition, goals, and healing potential.

You’ll receive a thorough evaluation through the integrated lenses of osteopathic, functional, regenerative, and rehabilitative medicine, along with a detailed physical exam where we assess not just the area of pain, but your entire musculoskeletal system, movement patterns, and functional limitations. Only then, with a complete and accurate diagnosis in hand, can we design the most effective regenerative treatment plan to help you heal and get back to the life you want to live.

Photo of a doctor treating a patients shoulder pain

Find Relief For Your Symptoms

Back pain relief, shoulder pain relief, knee pain relief…What are your symptoms?

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We are leaders in non-surgical relief for common problems and look at your pain from a holistic, comprehensive approach. We’re here to ensure you heal!

  • Neck Pain Treatment
  • Shoulder Pain Treatment
  • Elbow, Wrist & Hand Pain Treatment
  • Back and Spine Pain Treatment
  • Hip Pain Treatment
  • Knee Pain Treatment
  • Foot & Ankle Pain Treatment
  • Neuropathy Pain Treatment
  • Hypermobility Treatment

Physical Therapy Compliments our Regenerative Treatment

Regaining your function with Physical Therapy

Therapeutic exercise, designed to improve the patient’s function and decrease disability, differs from traditional exercise as it takes into account the patient’s pain, injuries, and functional impairments. Therapeutic exercise helps to improve the patient’s functional condition and general health, and it is a key part of comprehensive treatment at our practice.

Recent Blog Posts

Long-Term Results of PRP for Rotator Cuff Tears — Healing That Lasts – Two-Year Study

Study:A 2-year prospective study by Prodromos et al. (2021) examined patients with chronic rotator cuff tendinopathy and variable tears who had not improved with therapy. ...
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Perineural Platelet-Rich Plasma (PRP) for Diabetic Peripheral Neuropathy — Randomized Trial Shows Durable Benefit

Study:A prospective randomized clinical trial (Hassanien et al., Pain Medicine, 2020) evaluated ultrasound-guided perineural PRP for painful diabetic peripheral neuropathy (DPN). Sixty adults with type ...
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Adipose-Derived Stem Cells for Rotator Cuff Tears — MRI-Confirmed Tendon Regeneration and Long-Term Improvement

Study:A 2-year prospective study (Jo et al., Arthroscopy, 2020) evaluated the use of autologous adipose-derived stem cells (AD-MSCs) for partial-thickness rotator cuff tears. Nineteen patients ...
Read More →

Long-Term Results of PRP for Rotator Cuff Tears — Healing That Lasts – Two-Year Study

Study:A 2-year prospective study by Prodromos et al. (2021) examined patients with chronic rotator cuff tendinopathy and variable tears who had not improved with therapy. ...
Read More →

Perineural Platelet-Rich Plasma (PRP) for Diabetic Peripheral Neuropathy — Randomized Trial Shows Durable Benefit

Study:A prospective randomized clinical trial (Hassanien et al., Pain Medicine, 2020) evaluated ultrasound-guided perineural PRP for painful diabetic peripheral neuropathy (DPN). Sixty adults with type ...
Read More →

What Our Patients Say:

Anibal Vega
1 day ago
Very professional, they explained every detail of my treatment, it is a blessing that veterans help each others. Will definitely tell others, which already did to my relative that are suffering with back issue's, will go back for other treatments, thank you Dr. Sebastian.
⭐⭐⭐⭐⭐ Outstanding Care for Veterans – Life-Changing Results As a combat-wounded Iraq War veteran who served 29 years in the United States military, I have experienced many healthcare systems throughout my career and since my retirement. Without hesitation, I can say that Integrative Rehab Medicine provides the finest VA-covered medical care I have received in the last nine years. I would like to express my deepest gratitude to Dr. Sebastian Klisiewicz, his exceptional medical team, and Jason "JK" Kinnard, Chief Veteran Officer and Veteran Care Navigator, for their unwavering dedication to veterans and their families. Because of wounds and injuries sustained during my service in Iraq, I have suffered from multiple herniated discs in my spine as well as numerous joint-related conditions. Over the years, I underwent several surgeries, yet I continued to live with chronic pain that significantly affected my quality of life, sleep, mobility, and daily activities. From my very first interaction with Integrative Rehab Medicine, I knew I was in the hands of professionals who genuinely care about veterans. Dr. Klisiewicz took the time to thoroughly evaluate my conditions, explain treatment options, and develop a comprehensive plan focused on long-term improvement rather than temporary relief. After only two procedures—and while still in the recovery process before additional recommended treatments—I can already feel a remarkable difference. My pain levels have decreased significantly, my mobility is improving, and for the first time in years I am sleeping better and experiencing real hope for continued recovery. What truly sets this organization apart is not only their medical expertise but also their commitment to guiding veterans through the VA process. Jason "JK" Kinnard has been absolutely outstanding in helping navigate the system, ensuring that veterans receive the care they deserve with professionalism, compassion, and efficiency. His dedication to serving fellow veterans is extraordinary. Dr. Sebastian Klisiewicz and his entire team exemplify excellence in patient care. They listen, they care, and they deliver results. Their professionalism, compassion, knowledge, and commitment to improving veterans' lives are second to none. For any veteran seeking effective treatment for chronic pain, spinal injuries, joint issues, or rehabilitation services, I strongly recommend Integrative Rehab Medicine. They have helped me achieve progress that I had not experienced despite years of treatment elsewhere. Thank you, Dr. Klisiewicz, Jason "JK" Kinnard, and the entire Integrative Rehab Medicine team for your outstanding service to our veteran community. You are making a real difference in the lives of those who have sacrificed for our nation. Dr. Daniel Manrique, Ph.D. Combat-Wounded Iraq War Veteran Purple Heart Recipient Retired U.S. Military Officer
Alcalli Sabat
1 day ago
I had a lower back procedure performed with Interactive Rehab Medicine through the VA. The procedure "Discseel was a success but the VA side trying to get approved was a bumpy road and it's not the VA per say but the wrong people are in the process for approval and that needs to be fixed. I am healing well and the Staff from Interactive Rehab Medicine were very professional and I would recommend this procedure to any veteran with lower back issues in every aspect of outpatient and quick recovery. I still have 1 more month to go to completely heal so we will see. This procedure has made a difference in my life. Thank you Jason Kinnard, Dr. Sebastian Klisiewicz and all the Interactive Rehab Staff for a great job. Keep up the good work and I will be spreading the word. Are there any T-Shirts?
Isaac Cortes
1 day ago
Excellent services and staff unlike no other. Im now pain free from my back with no issues. Now would like to address my neck stiffness with PRP treatment injections when fully recovered from my March 19 postop neck revision surgery. Im confident that Dr. Klisiewicz will do a great job just like he did with my ailing back with the discseel procedure. See you soon Doc! 😊
brian feiock
2 days ago
I have found Dr. Klisiewicz to be a thoughtful, attentive, accurate, and highly skilled diagnostician/clinician. He performed a spinal disc procedure for me ("Discseel") which resulted in a remarkable degree of improvement in longstanding low back pain with minimal invasiveness, no complications, and a quick recovery. I completely trust his judgement, advice, and procedural capability. My experiences with he and his staff have been reliably positive. I recommend him highly and without reservation.
Carl
4 days ago
I had a great experience with Dr. Sebastian and the DISCSEEL procedure. From the consultation through follow-up care, he took the time to explain everything thoroughly and answer all of my questions. His professionalism, expertise, and genuine concern for his patients gave me confidence throughout the process. I also want to thank his staff for their outstanding care and support. I highly recommend Dr. Sebastian to anyone considering the DISCSEEL procedure.
Julie Wise
5 days ago
I went to Dr. Sebastian after having 1 year of primarily right sided back pain with mild radiation into my right calf. I wanted to avoid taking medication and surgery. I was active and working out at the gym, but limited in bending, lifting, and running. Dr. Sebastian felt confident my issue was related to an L5-S1 Disc issue and that the Discseel procedure would get me back to the activities that caused pain and eliminate my leg pain. I had my procedure on June 9, 2025 and every day of my life has been a nightmare ever since. The procedure has caused intense constant nerve pain and burning into both buttocks, thighs, and calves. It caused worse back pain. Simple daily tasks are challenging. Currently, 1 year later I am severely restricted from bending at all or I get increased burning down my legs. I cannot sit or lift. I cannot walk or stand more than 10 minutes. I have never been able to return to the gym. I have a physical job and I have only been able to work about half of the hours I had before. I am looking at quitting altogether because the hours I do work are excuciating. After unloading my bank account for this procedure, the financial effects of not being able to work are daunting. The physical and mental effects have been devastating. The symptoms have gradually worsened instead of improving and I now have neuropathy pain in my feet. I have had injections, medication, and a consult with a neurosurgeon since then. Discseel promised to keep me from these things, but instead has fast forwarded me toward them. Looking back, I think they told me about anything to convince me to do the procedure. When I wasn't getting the expected outcomes, they revealed that I had been mislead on many things. Prior to the procedure, he told me his patients do great with the procedure. Afterwards, he told me story after story of patients who had had failed procedures. Prior to the procedure, I was told that I had a greater than the average 85% success rate because I was young and active. Afterwards, Dr. Sebastian admitted that its actually been more of his younger more mobile patients who have had failed procedures. Prior to the procedure, I was told the fibrin was extremely strong and to follow the guidelines, but to not be overly stressed about my movements. Afterwards, Dr. Sebastian said that he has had patients feel a pop in their back and all their symptoms return just from bending over one time, coughing, or sitting on a plane flight. An MRI post procedure shows I have worse annular tearing and nerve compression at the segment treated than prior. Aside from something going wrong during the procedure itself, which I am told didnt, I was never warned in any capacity that Discseel could worsen nerve pain and cause worse annular tears and everyone needs to know how risky it is. Worst decision of my life having this done and I would give anything to be at the level of pain I was before I had it. To add insult to injury, after paying thousands of dollars for the procedure they billed my insurance for the follow ups and I was not aware of that. I got a letter saying they would send me to collections over $100 I didnt know I had missed paying. They are making bank off this and the results are not as good as they make you think. DON'T DO IT
Scott Phillips
2 months ago
Professional, caring, effective
Mel Schonhorst
3 months ago
Fantastic alternative to shoulder surgery. My torn tendon is now completely healed. Thank you Floyd, Kristine and your entire team.
David Yellen
3 months ago
Dr. Sebastian and Floyd helped me resolve my arthritic hip issue. I am able to run, sprint, lift weights and exercise intensely on the stair master. At our first meeting we developed a plan and then executed the plan. Everything fell into place from the first of two capsular distension shots. The third shot, a PRP injection just enhanced mobility and made stretching easier while providing a greater range of motion. I can't thank the IRM Team enough. If you have any type of physical injury, they are the best. They embrace helping athletes! Thanks again!