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PRP and Stem Cell Injections for Buttock Pain offered in Estero, Florida.

Do you suffer from nagging or sharp pain in your buttock that makes it hard to sit, walk, or enjoy daily activities?

Buttock pain can be especially frustrating because it often has more than one potential source. This results in patients going from doctor-to-doctor injection various locations to find the right target.

At Integrative Rehab Medicine, we understand that buttock pain is notoriously difficult to diagnose, which is why we use a comprehensive approach that combines a detailed physical examination with advanced imaging to uncover the true cause of your pain. After we identify the root causes of your buttock pain we will treat them with advanced non-surgical and regenerative therapies designed to restore tissue health and function.

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Common Symptoms of Buttock Pain

  • Deep, aching pain in the buttock, sometimes radiating to the thigh
  • Pain that worsens with prolonged sitting or walking
  • Tingling or numbness when nerve compression is involved
  • Weakness in surrounding muscles due to chronic irritation or instability

Causes of Buttock Pain

Buttock pain can stem from multiple structures, and often more than one issue contributes to the discomfort.

  • Hip Joint Problems – Conditions such as hip osteoarthritis (OA) or hip tendonitis/tendinopathy can cause localized buttock pain due to joint degeneration or small tendon tears that irritate surrounding tissues.
  • Sacroiliac (SI) Joint Dysfunction – Inflammation or instability of the SI joints, which connect the spine to the pelvis, often causes buttock pain that may mimic sciatica.
  • Lumbar Spine Nerve Compression – Spinal stenosis, herniated discs, or degenerative changes in the lumbar spine can compress nerves, leading to referred pain in the buttock.
  • Soft Tissue Injuries – Muscle strains or bursitis in the gluteal region may also contribute.

Because of these overlapping causes, proper diagnosis is essential to ensure effective treatment.

Accurate Diagnosis Is Key

At Integrative Rehab Medicine, we use a comprehensive diagnostic approach to identify the possible causes including spinal arthritis, stenosis, disc injury, tendon injury, tendonitis, hip arthritis and biomechanical dysfunction. This includes:

  • Comprehensive physical examination assessing the hip, spine, and SI joints
  • Ultrasound or MRI imaging to detect tendon tears, bursitis, disc injury or stenosis
  • X-rays to evaluate arthritis and joint space narrowing

This allows us to tailor a comprehensive regenerative treatment plan specific to your injury and functional goals.

There are treatment options for hip bursitis beyond repeated steroid injections.

Do You Want to Resolve Hip Pain and Restore Function?

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Regenerative Treatment Options

We specialize in non-surgical regenerative orthopedic solutions designed to stimulate the body’s natural healing processes and restore joint health. Our goal is to provide long-term pain relief by targeting the underlying cause of your buttock pain:

  • Platelet-Rich Plasma (PRP) – Uses your body’s growth factors to heal tendon tears, strengthen tissues, and reduce inflammation in the hip or SI joints. PRP can also be used to treat the facet joints of the spine or damaged/ inflamed nerves.
  • Prolotherapy – Stimulates repair and stabilizes ligaments around the pelvis, hips, and SI joints to restore function and reduce pain.
  • Stem Cell Therapy (Bone Marrow Derived) – Provides regenerative cells that can repair damaged cartilage, tendons, and ligaments for patients with arthritis or chronic injuries. 
  • Discseel – Discseel Procedure is an injection-based treatment that utilizes natural Fibrin glue to seal spinal discs. Disc tears are a common cause of chronic back and buttock pain. The Discseel® Procedure is the only treatment proven to seal spinal discs and encourage disc healing.

Frequently Asked Questions

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Are You a Candidate for Regenerative Hip Treatment

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Complementary Treatments

In addition to regenerative injections, we incorporate evidence-based complementary therapies to enhance recovery and long-term hip function:

  • 1-on-1 Physical Therapy – Work directly with a licensed physical therapist to strengthen and re-educate muscles of the hip and spine. This neuromuscular reprogramming helps restore movement patterns and reduce reinjury risk.
  • Nutritional Therapy & Supplements – Proper nutrition supports the healing of connective tissue. We offer personalized supplement protocols and dietary guidance to optimize collagen synthesis, reduce inflammation, and improve overall recovery.
  • Giga Laser Therapy – Our Giga Laser, one of the most powerful therapeutic lasers in the world, delivers high-dose red and infrared light therapy over large areas. This boosts mitochondrial activity and promotes rapid tissue healing and collagen formation.

Why Choose Integrative Rehab Medicine?

  • Minimally invasive treatments backed by clinical science
  • Comprehensive evaluation determining the root cause of your pain
  • Personalized regenerative treatment plans specific to your injury and functional goals
  • Avoid surgery and reduce downtime – many patients are back to activity 3-4 weeks after treatment
  • Expert clinicians with extensive experience in regenerative and rehabilitative medicine

Take Control of your Buttock Pain

Buttock pain can interfere with your ability to sit comfortably, stay active, or even sleep. With accurate diagnosis and advanced regenerative treatments, you don’t have to live with this discomfort.

Schedule your consultation today with Integrative Rehab Medicine and take the first step toward long-lasting relief.

Schedule your Consult with an Estero Hip Pain Specialist

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References

  1. Dallari D, Stagni C, Rani N, et al. Ultrasound-Guided Injection of Platelet-Rich Plasma and Hyaluronic Acid, Separately and in Combination, for Hip Osteoarthritis: A Randomized Controlled Study. The American Journal of Sports Medicine. 2016;44(3):664-671. doi: 10.1177/0363546515620383
  2. Fitzpatrick J, Bulsara MK, O’Donnell J, Zheng MH. Leucocyte-Rich Platelet-Rich Plasma Treatment of Gluteus Medius and Minimus Tendinopathy: A Double-Blind Randomized Controlled Trial With 2-Year Follow-up. Am J Sports Med. 2019 Apr;47(5):1130-1137. doi: 10.1177/0363546519826969. Epub 2019 Mar 6. PMID: 30840831.
  3. Fitzpatrick J, Bulsara MK, O’Donnell J, McCrory PR, Zheng MH. The Effectiveness of Platelet-Rich Plasma Injections in Gluteal Tendinopathy: A Randomized, Double-Blind Controlled Trial Comparing a Single Platelet-Rich Plasma Injection With a Single Corticosteroid Injection. Am J Sports Med. 2018 Mar;46(4):933-939. doi: 10.1177/0363546517745525. Epub 2018 Jan 2. PMID: 29293361.
  4. Giorgino, R., Alessandri Bonetti, M., Migliorini, F. et al. Management of hip osteoarthritis: harnessing the potential of mesenchymal stem cells—a systematic review. Eur J Orthop Surg Traumatol 34, 3847–3857 (2024). https://doi.org/10.1007/s00590-024-04089-0
Integrative Rehab Medicine
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Julia Neis
I have seen spinal surgeons, orthopedic surgeons, neurologists, and gotten trigger point injections. Nothing made my chronic low back pain better. Once I went to Dr. Sebastian and his clinic, they reviewed my MRIs and X-Rays, did a physical assessment, and quickly identified my issue in the first visit. I was hesitant to continue with the PRP procedure in my pelvis and low back, since I have been in constant pain for 11 months and had many failures with injections. I am now a little over 2 months post-PRP procedure, back to running and lifting with no pain. I am extremely grateful for Dr. Sebastian and his entire staff, who were welcoming and supportive every day I came into the clinic!
Response from the owner:Thank you for trusting Integrative Rehab Medicine in Estero, Florida with your back pain care. We understand how discouraging chronic low back pain can be after seeing multiple specialists without relief. We’re glad that a comprehensive assessment allowed Dr. Sebastian Klisiewicz to identify the source of your, and better yet, an effective back pain treatment with PRP injections and specific rehabilitation. Hearing that you’re back to running and lifting pain-free just over two months after your PRP procedure is incredibly rewarding. Our team is committed to providing care in a safe environment while supporting our patients every step of the way. We’re grateful to be part of your recovery and wish you continued health and strength.
Chris Drikakis
I am currently one month removed from my procedure from Dr. Sabastian and his staff. All of my consistent pain stop. Physical therapy is continuing under there direction.

With more positive improvement coming long term my advice why wait call or visit them. Integrative Rehab Medicine is the very best non-surgical treatment of the spinal discs.

I excited about my future living without pain. Make this appointment your health will Thank you later.

Chris Drikakis
A fellow golfer and Vietnam veteran
Response from the owner:Thank you so much, Chris, for taking the time to share your experience—and for your service as a Vietnam veteran. We’re truly honored to be part of your healing journey.

We’re thrilled to hear that just one month after your non-surgical spinal disc procedure, your consistent pain has resolved and that you’re continuing to make progress. At Integrative Rehab Medicine, our mission is to help patients avoid unnecessary spine surgery by offering advanced, evidence-based treatments for chronic back and neck pain, including non-surgical disc repair options such as Discseel® and PRP.

Your story highlights exactly why we focus on treating the underlying cause of disc-related pain—not just masking symptoms—and why so many active patients, including golfers and veterans, seek out non-operative spine care with us. We’re excited about your continued improvement and long-term recovery.

https://irehabmed.com/va

Thank you again for your kind words.
David OBrien
As a medical professional ( anesthesiology) for 40 years Dr Sebastian helped me avoid debilitating back surgery with a six week recovery ( which I scheduled for ) two weeks before my Ozone/ lysated platelet epidural. I am beyond the moon happy with my results. His office is very professional and his PT therapist Christine is also excellent !
Response from the owner:Thank you so much for sharing your experience. Coming from a medical professional with over 40 years in anesthesiology, your perspective truly means a great deal to our entire team.
We’re thrilled to hear that your ozone intradiscal treatment combined with lysated platelet (PRP) epidural injections helped you avoid a major back surgery and a prolonged recovery. At Integrative Rehab Medicine, we love helping patients with herniated and bulging discs find effective, non-surgical alternatives to spine surgery.
Your outcome highlights the power of biologic and regenerative spine treatments—using ozone to reduce disc inflammation and herniation, along with platelet-based therapies to support healing around irritated spinal nerves. We’re also glad to hear your experience with Kristine, our physical therapist, has complemented your recovery.
Thank you again for your words and confidence in our team.
Hernan Mota
Im very fortunate to met the Doctor Sebastian when he came to Margaritaville Cancun riviera Maya. He treated my knee after two surgeries in my right knee without result. The time Doctor Sebastian attended me I was in pain every day and taking anti inflammatory every 2 days, since he treated me my knee and movement change drastically at level I don’t taking any more medication he is a really master pro, for sure I’ll will see him early next year for a second treatment to keep improving my recovery thanks Doctor to came across my live 🙏🙏🙏🙏Hernan Mota
Tom and Margie Hurwich
I had suffered from degenerating discs, bulging discs and arthritis in my lower back for 25 years. I initially went to Integrative Rehab Medicine as they offered DiscSeel, which I heard was a great option for me. Although I was a candidate for this, I opted for PRP and prolotherapy. My recovery was a bit longer than o hoped at 8-12 weeks but I am finally pain free and only get discomfort for a day or so with movements that may have had me down for 2 months. The care in office was wonderful with great follow ups. They also allowed my personal trainer into my physical therapy to ensure we were on the same page with my recovery. Five stars and I would highly recommend.
Response from the owner:Thank you so much for sharing your journey. We truly appreciate your trust after living with degenerative discs, bulging discs, and lumbar arthritis for more than 25 years.
While Discseel® can be an excellent option for certain patients, we’re glad you found success with platelet-rich plasma (PRP) and prolotherapy—two powerful non-surgical treatments designed to reduce inflammation, support tissue healing, and improve spinal stability. As you experienced, biologic spine treatments often require patience, with healing occurring over weeks to months, but the long-term improvement can be life-changing.
We’re especially happy to hear that you’re now pain-free and that movements which once caused months of setback now result in only brief, mild discomfort. That kind of functional recovery is exactly what we aim for at Integrative Rehab Medicine.
We truly appreciate the recommendation and are honored to be part of your long-term spine health.
Genko Ganev
I’m so glad that I found Integraive Rehab Medicine and specifically Dr Sebastian. Dr Sebastian was the only doctor who provided a solution to my damaged lower back that made sense and actually worked. After six months after the procedure I can say that Dr Sebastian gave me back the ability to move pain free and enjoy life as I could at my age. He said he is sorry that he couldn’t make me young again, but he and his staff did a miracle for me.
Thank you Integrative Rehab Medicine for changing my life
Response from the owner:Thank you for sharing your experience and for allowing us to play a role in your healing. We are truly grateful that you put your trust in our regenerative medicine approach to treating back pain and improving function. Helping patients feel stronger and more functional is what we do best here at Integrative Rehab Medicine in Estero, Florida. Take care.
Egor Kelman
A true professional, Dr. Sebastian immediately identified my problem and recommended additional injections, which started working literally the next day. I felt initial relief in an area that had been in spasm for the past eight years.
Response from the owner:Thank you so much for sharing your experience! I’m thrilled to hear that you felt relief so quickly after your treatment. Our goal at Integrative Rehab Medicine in Estero, Florida is always to identify the true source of pain and deliver precise, non-surgical solutions that help our patients finally move and live without chronic muscle spasms or pain.
It’s wonderful to see your body responding and healing after so many years. Thank you for trusting us with your care!
Maggie Castro
From the moment I walked in, I was treated with genuine warmth and respect. The entire team from the front desk staff to the nurses and Dr Floyd & Dr Sebastian were incredibly attentive and professional. They took the time to understand my concerns, explain the treatment plan thoroughly, and ensure all my questions were answered. I never felt rushed. I received calls & emails to check on my progress, ensuring that everything was going smoothly after my visit. I have done PRP & the discseel procedure. It has been a few months now and I am heeling well. Thank you so much to the entire Team!
Response from the owner:Thank you, Maggie, for your wonderful review and for trusting our team with your care! We’re so glad to hear that you felt supported throughout your PRP and Discseel treatments and that your healing is progressing well. At Integrative Rehab Medicine in Estero, Florida, our entire team — from the front desk to the nurses and physicians — is dedicated to providing personalized, compassionate, and regenerative care that helps each patient truly heal.
We appreciate you sharing your experience and are honored to be part of your recovery journey!
Robert Long
I have not been here but I have seen Dr. Shiple in PA. He is one of the world's most flawless injectors! From PRP, Stellate Ganglion Block, Vagus Nerve Block, Hydrodissection etc...

He has gotten me out of a bedbound life.

He does even better when Bruce Hornsby is playing during the session 😁
Response from the owner:Thank you for sharing such kind words about Dr. Brian Shiple! He is indeed one of the most skilled and experienced regenerative injection specialists in the world, and we’re honored to have him on our team here at Integrative Rehab Medicine in Estero, Florida. It’s inspiring to hear how his advanced techniques—like PRP, Stellate Ganglion Block, Vagus Nerve Block, and ultrasound-guided hydrodissection—helped you reclaim your health and quality of life.
Patrick Gendreau
Dr. Sebastian and his team conducted a thorough review of my MRI, scheduled a Zoom consultation, and performed this transformative procedure—all within one month of my initial inquiry. The procedure was carried out at a state-of-the-art facility, which I would rate as exceptional.

Two months post-procedure, my lower back pain has improved by approximately 95%. Although I still have four months remaining in my recovery timeline, I already feel like a new person. I am now able to sleep comfortably, drive, and sit for extended periods without experiencing persistent discomfort or pain.

I highly recommend scheduling an MRI review to determine whether this procedure may be appropriate for individuals suffering from sciatica, degenerative disc disease, herniated discs, or other spinal issues. This technique represents a remarkable advancement in treatment.

— Patrick G
Response from the owner:Patrick, thank you for trusting us with your care here at our Estero FL clinic. We’re thrilled to hear how much relief from your back pain you’ve experienced just two months after your spine treatment. At Integrative Rehab Medicine, our team is committed to providing thorough diagnostics, from spinal MRI review to personalized in person and telehealth consultations, and delivering advanced regenerative treatments for sciatica, degenerative disc disease, herniated discs, and other spinal conditions. It’s wonderful to know our state-of-the-art facility and approach made such a difference for you. We truly appreciate your recommendation and look forward to supporting you throughout your recovery journey.