Evidence-based updates from the experts at Integrative Rehab Medicine

Long-Term Results of PRP for Rotator Cuff Tears — Healing That Lasts – Two-Year Study

Study:A 2-year prospective study by Prodromos et al. (2021) examined patients with chronic rotator cuff tendinopathy and variable tears who had not improved with therapy. ...
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Perineural Platelet-Rich Plasma (PRP) for Diabetic Peripheral Neuropathy — Randomized Trial Shows Durable Benefit

Study:A prospective randomized clinical trial (Hassanien et al., Pain Medicine, 2020) evaluated ultrasound-guided perineural PRP for painful diabetic peripheral neuropathy (DPN). Sixty adults with type ...
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Adipose-Derived Stem Cells for Rotator Cuff Tears — MRI-Confirmed Tendon Regeneration and Long-Term Improvement

Study:A 2-year prospective study (Jo et al., Arthroscopy, 2020) evaluated the use of autologous adipose-derived stem cells (AD-MSCs) for partial-thickness rotator cuff tears. Nineteen patients ...
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Bone Marrow Stem Cells are a Non-Surgical Option for Rotator Cuff Tears — with Sustained 2-Year Improvement

Study:A randomized controlled crossover trial (Centeno et al., 2020) compared ultrasound-guided injections of autologous bone marrow concentrate (BMC) combined with PRP to a structured home ...
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Ozone for Lumbar Disc Herniation — High-Volume Study Supports a Safe, Minimally Invasive Option

For patients with lumbar and cervical disc herniations, ozone disc nucleolysis offers a targeted, image-guided solution to reduce disc pressure and inflammatory radiculopathy without surgery. ...
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Fibrin Discseel Procedure Demonstrates Long-Term Back Pain and Sciatica Relief Through Disc Healing — 3-Year Study Results

Study:A landmark study published in Pain Physician (Pauza et al., 2024) evaluated 827 patients with chronic low back pain lasting over six months (average duration ...
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