PRP and Stem Cell Injections for Knee Arthritis offered in Estero, Florida

Struggling with Knee pain and loss of Range of Motion? You may have Knee Arthritis.

If you’re experiencing chronic knee pain, stiffness, or limited range of motion, you may be suffering from knee osteoarthritis— a degenerative joint condition that can significantly affect your daily life.

At Integrative Rehab Medicine, we specialize in non-surgical regenerative orthopedic solutions that not only help manage pain but also target the root causes of joint degeneration—helping you stay active and avoid or delay surgery.

What Is Knee Osteoarthritis?

Osteoarthritis (OA) of the knee is a degenerative joint condition where the cartilage cushioning the knee gradually wears down. Over time, the joint may become less flexible, making daily
activities like walking, climbing stairs, or standing for long periods more challenging.

Knee arthritis often develops due to aging, repetitive use, past injuries, or genetic predisposition. When people have arthritis, many times they are also dealing with laxity of the supporting ligaments and tendons as well as weakness in muscles leading to poor biomechanics.

Symptoms of Knee Arthritis (Osteoarthritis)

  • Aching or sharp pain in the knee, especially after activity
  • Stiffness, particularly in the morning or after sitting
  • Swelling and inflammation around the joint
  • Clicking, grinding, or popping sensations
  • Loss of flexibility and range of motion
  • Pain that worsens with weight-bearing activities

Accurate Diagnosis Is Key

At Integrative Rehab Medicine, we use a comprehensive diagnostic approach to identify the extent of cartilage loss, inflammation, and biomechanical dysfunction. This includes: 

  • Detailed orthopedic examination and movement testing
  • Imaging such as X-rays, ultrasound, and MRI to evaluate joint space, bone spurs and soft tissues
  • Functional strength and posture assessments to guide treatment

This allows us to tailor a comprehensive regenerative treatment plan specific to your injury and functional goals.

Contrary to popular opinion not all knee arthritis needs to be treated surgically. Many patients can be effectively treated non-surgically with regenerative injections.

Are You a Candidate for Non-Surgical Knee Pain Treatment?

Regenerative Treatment Options

We specialize in non-surgical regenerative orthopedic solutions designed to stimulate the body’s natural healing processes and restore joint health.

  • Prolotherapy

Prolotherapy uses targeted injections of dextrose to stimulate healing. When administered at the right concentration, the solution triggers a mild, temporary inflammatory response activating fibroblasts specialized cells that produce collagen to strengthen and thicken the surrounding ligaments and tendons, ultimately improving knee stability and support.

  • Platelet-Rich Plasma (PRP) Therapy

Platelet-Rich Plasma (PRP) contains growth factors that accelerate tissue repair. PRP injections can reduce inflammation, improve collagen remodeling, and promote long-term healing of the joint. PRP works best for mild to moderate arthritis

  • Stem Cell Therapy

We utilize Bone Marrow Stem Cells to support tissue regeneration and repair, particularly for more severe knee arthritis. Through the release of growth factors, stem cells regulate the local immune response, decrease inflammation and stimulate tissue growth. Stem cells have been shown to be very effective for treating knee osteoarthritis even in patients with moderate to severe arthritis.

Do You Want to Resolve Knee Pain and Restore Function?

Complementary Treatments

In addition to regenerative injections, we incorporate evidence-based complementary therapies to enhance recovery and long-term knee function:

1-on-1 Physical Therapy

Work directly with a licensed physical therapist to strengthen and re-educate the muscles of the knee, hip and ankles to increase stability. This neuromuscular reprogramming helps restore movement patterns and reduce reinjury risk.

Nutritional Therapy & Supplements

Proper nutrition supports the healing of connective tissue. We offer personalized supplement protocols and dietary guidance to optimize collagen synthesis, reduce inflammation, and improve overall recovery.

Giga Laser Therapy

Our Giga Laser, one of the most powerful therapeutic lasers in the world, delivers high-dose red and infrared light therapy over large areas. This boosts mitochondrial activity and promotes rapid tissue healing and collagen formation.

Why Choose Integrative Rehab Medicine?

  • Minimally invasive treatments backed by clinical science
  • Comprehensive evaluation determining the root cause of your pain
  • Personalized regenerative treatment plans specific to your injury and functional goals
  • Avoid surgery and reduce downtime – many patients are back to activity 3-4 weeks after treatment

Expert clinicians with extensive experience in regenerative and rehabilitative medicine

Get Back to an Active Life

Knee arthritis doesn’t have to mean giving up the activities you love. With the right regenerative and supportive care, you can move more comfortably, improve joint function, and avoid or delay surgery. Schedule a consultation today to explore your non-surgical options for knee arthritis relief.

Schedule Your Consult with an Estero Knee Pain Specialist

References

  • Centeno, Christopher, et al. “Image Guided Injection of Anterior Cruciate Ligament Tears with Autologous Bone Marrow Concentrate and Platelets: Midterm Analysis from A Randomized Controlled Trial.” Biologic Orthopedics Journal 3.SP2 (2021): e7-e20.
  • Hernigou P, Auregan JC, Dubory A, Flouzat-Lachaniette CH, Chevallier N, Rouard H. Subchondral stem cell therapy versus contralateral total knee arthroplasty for osteoarthritis following secondary osteonecrosis of the knee. Int Orthop. 2018 Nov;42(11):2563-2571. doi: 10.1007/s00264-018-3916-9. Epub 2018 Mar 27. PMID: 29589086.
  • Kim JD, Lee GW, Jung GH, Kim CK, Kim T, Park JH, Cha SS, You YB. Clinical outcome of autologous bone marrow aspirates concentrate (BMAC) injection in degenerative arthritis of the knee. Eur J Orthop Surg Traumatol. 2014 Dec;24(8):1505-11. doi: 10.1007/s00590-013-1393-9. Epub 2014 Jan 8. PMID: 24398701.
  • Pabinger, C., Lothaller, H. & Kobinia, G.S. Intra-articular injection of bone marrow aspirate concentrate (mesenchymal stem cells) in KL grade III and IV knee osteoarthritis: 4 year results of 37 knees. Sci Rep 14, 2665 (2024). https://doi.org/10.1038/s41598-024-51410-2
  • Tavassoli M, Janmohammadi N, Hosseini A, Khafri S, Esmaeilnejad-Ganji SM. Single- and double-dose of platelet-rich plasma versus hyaluronic acid for treatment of knee osteoarthritis: A randomized controlled trial. World J Orthop. 2019 Sep 18;10(9):310-326. doi: 10.5312/wjo.v10.i9.310. PMID: 31572668; PMCID: PMC6766465.
  • Wijn, S. R. W., Rovers, M. M., van Tienen, T. G., & Hannink, G. (2020). Intra-articular corticosteroid injections increase the risk of requiring knee arthroplasty. The Bone & Joint Journal, 102-B(5), 586–592. doi:10.1302/0301-620x.102b5.bjj-2019-1376.r1