Study:
A randomized controlled crossover trial (Centeno et al., 2020) compared ultrasound-guided injections of autologous bone marrow concentrate (BMC) combined with PRP to a structured home exercise program for patients with partial and full-thickness supraspinatus tears who had failed at least 3 months of conservative care.
Patients were followed for up to 24 months using DASH (function), Numeric Pain Scale (NPS), and blinded MRI review.
Results:
- The BMC group showed significant improvement in pain and function by 3 months, with continued gains at 6, 12, and 24 months.
- Patients reported an average of 89% overall improvement at 24 months (SANE).
- MRI review showed most tears had decreased in size after BMC treatment (14 of 15 scans favored the post-treatment tendon).
- No serious adverse events; most exercise-only patients chose to cross over to BMC.
Key Takeaway:
Ultrasound-guided Bone Marrow Stem Cells combined with PRP provides durable pain relief, functional recovery, and MRI-demonstrated tendon healing for partial and full-thickness supraspinatus tears—offering a safe, non-surgical alternative when standard conservative care is not enough.
At Integrative Rehab Medicine, our bone marrow–derived stem cell treatments are delivered under exact image guidance to target tendon and joint pathology with exceptional accuracy. We partner closely with local physical therapists to integrate healing with structured rehabilitation, supporting strength, motion, and durable functional recovery.
Reference:
Centeno, C. et al., Stem Cells International (2020).
https://doi.org/10.1155/2020/5962354