Dr. Brian J. Shiple, D.O., CAQSM, RMSK
Interventional Regenerative Orthopedic Medicine Specialist
Sports Medicine Physician in Estero, FL (Between Fort Myers, Bonita Springs, and Naples)
Leading Expert in Regenerative Spine & Joint Treatments
A National Leader in Regenerative Orthobiologics & Non-Surgical Sports & Spine Injury Care
Dr. Brian Shiple is a nationally renowned physician specializing in non-surgical orthopedic and spine care, regenerative medicine, and sports medicine. With over 30 years of experience, he is a pioneer in ultrasound- and fluoroscopy-guided biologic injections, including Bone Marrow Stem Cells (BMC), Platelet-Rich Plasma (PRP), Adipose Fat Grafts, Discseel ®, Ozone, Amniotic Tissue Grafts, Umbilical Cord Derived Stem Cells, Exosomes, Prolotherapy and more.
He is best known for helping patients—and athletes of all levels—avoid surgery and return to peak performance. His reputation for excellence draws patients from across the U.S. and abroad, seeking his minimally invasive treatments that stimulate the body’s natural healing.
Sports & Spine Medicine Expertise
As a board-certified sports medicine physician in Florida, Dr. Shiple has treated thousands of athletes, from high school competitors to professional and Olympic-level performers. He has served as:
- Team Physician to multiple high school districts in Delaware County Pennsylvania
- Chief Medical Officer– Pennsylvania Senior Games (1994-2007)
- Volunteer Physician – U.S. Olympic Training Center, Colorado Springs
- Founding Medical Director – Philadelphia Triathlon at Fairmount Park
- Founder and Director of Crozer Keystone Health System Sports Medicine Fellowship program from 1994 to 2007 Springfield, PA
- Medical Director USOC Training and Testing Center Springfield Healthplex, Springfield, PA 1995-2007
He is a recognized expert in treating sports and spine injuries:
- Rotator Cuff and Labrum Tears & Other Shoulder Injuries
- Knee Injuries such as Meniscus & ACL/MCL Tears
- Shoulder, Elbow, Wrist, Hip, Knee and Ankle Arthritis
- Tendonitis, Ligament Sprains, Muscle Strains and Chronic Overuse Injuries
- Herniated, Bulging and Degenerative Torn Discs
- Sciatica, SI Joint Pain and other Spine Conditions
- Nerve Entrapment and Peripheral Nerve Injuries
Dr. Shiple uses regenerative injections like Platelet-Rich Plasma (PRP), Bone Marrow Stem Cells (BMC), Discseel ® Procedure, Exosomes, Nerve Hydrodissection and other image-guided techniques to help athletes and professionals heal their injuries naturally, avoid invasive surgery and return to an active lifestyle.
Innovations in Regenerative Orthopedics and Spine Care
- Creator of SpineRenu® – Orthobiologic protocol using PRP, bone marrow, and concentrated plasma for discogenic back and neck pain
- Developer of JointRenu® – Non-surgical solutions for arthritis and joint damage
- Discseel® Procedure Provider– Treats disc tears, herniations and degeneration with FDA-approved fibrin glue
- Developer and Medical Director of Stem Cell International– Takes patients to Cancun Mexico to have Umbilical Cord Derived culture Expanded Mesenchymal Stem Cells and Exosomes to treat his patients orthopedic and medical conditions with cutting edge strong allogenic stem cells and exosomes which are restricted from being used in the USA. 2016- Current
Leadership & Education
- Past President – American Academy/ Association of Orthopaedic Medicine (AAOM)
- Former Division Chief of Sports Medicine and founder of the Sports Medicine Fellowship at Crozer-Keystone Health System in Pennsylvania (1994–2007)
- Internationally Recognized Educator – Has spoken at over 100 national and international conferences and trained over 1,000 physicians from 18 countries in regenerative medicine
- Founding Board Member – International Cellular Medicine Society
- Former Regenexx Affiliate – Among the first in the U.S. to adopt stem cell therapy for orthopedic conditions
Recognized Author, Speaker & Innovator
- Author: Regenerative Healing for Life (2013)
- Featured on PBS, ESPN, and Philly Magazine’s “Top Docs”
- Speaker at global conferences: ICRS, AMSSM, Korea, Hong Kong, and more
- Contributor to PRP nomenclature research published in PM&R journal (2015)
- Lead researcher for Orthovi, LLC on stem cell-based spine and knee protocols
Offering Treatments at Integrative Rehab Medicine – Estero, Florida
Dr. Shiple has joined Integrative Rehab Medicine in Estero, Florida to bring his cutting-edge approach to patients in Southwest Florida and across the U.S. Whether you’re an athlete recovering from injury or someone seeking relief from chronic joint or spine pain, Dr. Shiple offers world-class care with real results—without surgery.
